Summary sectionCognitive and behavioural recommendations: R50: Hyper- and hyposensitivity and other sensory processing difficulties should be assessed, and support strategies should be implemented in individuals with CdLS throughout their lifespan. R51: Increasing adaptive skills to enhance independence should remain a focus throughout the lifespan and should include personalised specific goals and teaching strategies. R52: Additional developmental and educational support should be provided to individuals with CdLS to reach their maximum cognitive and educational potential, taking into account their specific cognitive impairments. R53: Cognitive strengths and weaknesses of individuals with CdLS should be assessed in order to design educational and interventional strategies. R54: To identify the cause of self-injurious behaviour in individuals with CdLS, medical assessment, specifically looking for sources of pain, should be followed by behavioural assessment of self-restraint then functional analysis. R55: Treatment of self-injurious behaviour should include both medical and behavioural strategies. R56: A clinical diagnosis of autism spectrum disorder (ASD) should be considered in all individuals with CdLS throughout life, taking into account atypical presentations. R57: In addition to standardised ASD diagnostic tools, fine-grained observations should be carried out to accurately define the profile of social functioning in an individual with CdLS. R58: ASD-specific interventions should be considered in all individuals with CdLS in combination with approaches that consider the broader social functioning profile of the syndrome. R59: Interventions targeting problematic repetitive behaviour in individuals with CdLS should be sensitive to anxiety, sensory problems and social demands. These interventions should also consider environmental factors. R60: Atypical presentation of anxiety and mood disorder should be considered when behaviour changes occur. R61: As anxiety is common in individuals with CdLS during periods of environmental change/transitions, a planned program should be implemented. R62: Treatment of anxiety and mood disorders in individuals with CdLS should be considered using psychosocial interventions (therapies) and pharmacotherapy (medication). R63: When assessing communication, vision and hearing problems, speech impairments, intellectual disability, difficulties in social interaction and social anxiety should be considered. Video observations can be very useful. R64: Developmentally appropriate communication strategies (such as speech therapy, augmented communication input) should be implemented within the first 18 months of life. |